rx-sexualhealth.com

Überlube Review

Updated 2026-10-02 · 2 min read · Sources linked in the text

Our verdict

Überlube is an unscented silicone lubricant cleared by FDA. Its 510(k) record lists it as compatible with natural rubber latex and polyisoprene condoms but not polyurethane ones, and no independent lab or clinical data on the product itself were found, so it ranks just behind the cheaper Wet Platinum.

$21.99 ($11.82 / fluid ounce)

Amazon price as of Oct 3

Best for

  • People who want glide that lasts without reapplying
  • Use with latex or polyisoprene condoms (per its 510(k) record)

Skip it if

  • You use polyurethane condoms — its 510(k) record says it is not compatible with them
  • You prefer a product that washes off with water alone
  • You are using silicone devices that the maker says not to pair with silicone lubricant
Überlube key facts
Active ingredientNone (silicone-based personal lubricant)
FormSilicone liquid lubricant (FDA 510(k) K151647)
OnsetImmediate
How to useApply as needed before or during sex
AgesAdults
Exact itemÜberlube silicone lubricant, unscented, 55 ml
Price$21.99 ($11.82 / fluid ounce) (amazon price as of oct 3)

How we got 3.8

3.8
Evidence grade B (moderate evidence). Water- and silicone-based lubricants were linked to higher sexual pleasure and few genital symptoms in a 2,453-woman prospective study (PMID 21143591), and guidelines recommend silicone- or water-based lubricants for dryness, pain with sex and condom users (PMID 32852449, 40730448). FDA 510(k) K151647 covers Überlube and lists it as compatible with natural rubber latex and polyisoprene condoms but not polyurethane condoms. In that study genital symptoms were rare, but water-based products were linked to fewer of them than silicone.
±0.0
Practical adjustment. Long-lasting silicone glide and unscented; costs more per ml than water-based options.

Scores are calculated, not hand-picked: evidence first, with a small adjustment for side effects, convenience, and value. How we rate

What Überlube is

Überlube is a silicone-based personal lubricant. Its FDA 510(k) summary describes it as "a clear, colorless, semi-viscous silicone-based personal lubricant", usually sold in glass bottles with pump tops. FDA cleared it in 2015 (FDA 510(k) K151647) under the classification "Lubricant, Personal" (FDA product classification NUC).

On condoms, the record is specific. Testing to the ASTM D7661-10 standard found Überlube compatible with natural rubber latex and polyisoprene condoms, and not compatible with polyurethane condoms (FDA 510(k) K151647). That matters because polyurethane is one of the latex-free condom options.

Silicone lubricant evidence

No published study of Überlube itself was found, so the evidence is for silicone lubricants as a class. In a five-week double-blind diary study of 2,453 women assigned one of six water- or silicone-based lubricants, lubricant use was associated with higher sexual pleasure and satisfaction and was rarely associated with genital symptoms, though water-based products were associated with fewer symptoms than silicone ones PMID: 21143591. In 2012 laboratory testing, both silicone-based lubricants tested (not Überlube) were among the safest for cells and tissue samples PMID: 23144863. A family-medicine review recommends silicone- or water-based lubricants for condom users PMID: 40730448.

Who Überlube suits

Consider Überlube if you want an unscented silicone lubricant and use latex or polyisoprene condoms, or none.

Consider Wet Platinum if you use polyurethane condoms or want a cheaper silicone option with independent lab data. Consider Good Clean Love Almost Naked if you prefer a water-based product. Our guide to the best personal lubricants explains how to choose.

Pros

  • Compatible with natural rubber latex and polyisoprene condoms, per its FDA 510(k) record
  • Unscented
  • FDA 510(k) K151647

Cons

  • Not compatible with polyurethane condoms, per its 510(k) record
  • Costs more per ml than our other picks
  • No independent lab or clinical data on this product were found
  • In a large diary study, water-based lubricants were linked to fewer genital symptoms than silicone ones, though symptoms were rare overall

Überlube

Überlube silicone lubricant, unscented, 55 ml

How it compares

ProductScoreOnsetBest for
Überlube (this review)3.8 · BImmediatePeople who want glide that lasts without reapplying
Good Clean Love Almost Naked3.8 · BImmediatePeople who want a brand with near-iso-osmolar lab data (variant tested not named)

Frequently asked questions

Is Überlube FDA cleared?

Yes. FDA cleared Überlube through the 510(k) process (K151647) in 2015 under the device classification 'Lubricant, Personal'.

Can I use Überlube with condoms?

With latex and polyisoprene condoms, yes, according to its FDA 510(k) record. The same record says it is not compatible with polyurethane condoms, so choose a different lubricant if you use those.

Is Überlube water-based?

No. Its 510(k) summary describes it as a clear, colorless, semi-viscous silicone-based lubricant.

Is Überlube worth the price?

It depends on what you value. It is an unscented, FDA-cleared silicone lubricant, but Wet Platinum is cheaper, has independent lab safety data and is listed as compatible with polyurethane condoms as well.

Sources

Advertising disclosure: We earn a commission when you buy through links on this page, at no extra cost to you. It never changes our rankings. See our full disclosure.